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Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

Proglucagon (D16G10) XP® Rabbit mAb #8233

Filter:
  • IHC
  • IF
Immunohistochemical analysis of paraffin-embedded human pancreas using Proglucagon (D16G10) XP® Rabbit mAb.

To Purchase # 8233

Cat. # Size Qty. Price
8233T 20 µl
$155
8233S 100 µl
$371

Product Specifications

REACTIVITY H M R
SENSITIVITY Endogenous
MW (kDa)
Source/Isotype Rabbit IgG
Application Key:
  • IHC-Immunohistochemistry 
  • IF-Immunofluorescence 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Immunohistochemistry (Paraffin) 1:400
Immunofluorescence (Frozen) 1:400

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

For a carrier free (BSA and azide free) version of this product see product #29302.

Protocol

Specificity / Sensitivity

Proglucagon (D16G10) XP® Rabbit mAb recognizes endogenous levels of total proglucagon protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala137 of human proglucagon protein.

Background

Glucose homeostasis is regulated by a variety of hormones including glucagon. Glucagon is synthesized as the precursor molecule proglucagon and is proteolytically processed to yield the mature peptide in α cells of the pancreatic islets. Glucagon causes the release of glucose from glycogen and stimulates gluconeogenesis in the liver (1,2).

Alternate Names

GCG; Glicentin; Glicentin-related polypeptide; GLP; GLUC; Glucagon; Glucagon-like peptide 1; GRPP; OXM; OXY; Oxyntomodulin

For Research Use Only. Not for Use in Diagnostic Procedures.
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