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InTraSeq Single Cell Analysis: A Multimodal Single-Cell Method for Simultaneous Measurement of RNA and Proteins to Uncover New Single-Cell Biology

 

Single-cell RNA sequencing (scRNA-seq) is a powerful technique for studying the molecular heterogeneity of cells. However, scRNA-seq does not provide information about protein expression, which is essential for understanding the functional state of cells. In this video, we introduce InTraSeq Single Cell Analysis, a novel technology developed by Cell Signaling Technology (CST). InTraSeq (Intracellular Protein and Transcriptomic Sequencing) enables the concurrent measurement of RNA, surface markers, cytoplasmic proteins, and nuclear proteins within individual cells. By leveraging renowned CST® antibodies, InTraSeq Single Cell Analysis also enables the study of signaling pathways at single-cell resolution. Developed and validated by CST, InTraSeq 3’ technology uses the 10x Genomics Chromium Single Cell 3’ Reagent Kits with Feature Barcoding technology.

Cell Signaling Technology, CST, and InTraSeq are trademarks of Cell Signaling Technology, Inc. All rights reserved. 10x Genomics, 10x, Feature Barcode, and Chromium are the trademarks or registered trademarks of 10x Genomics, Inc. All other trademarks are the property of their respective owners. Visit cellsignal.com/trademarks for more information.
Subject to patents licensed from 10x Genomics, Inc., for use with single-cell (i.e., Chromium) 10x products.