Render Target: STATIC
Render Timestamp: 2025-01-21T04:31:02.529Z
Commit: da7e4f2f0d1aed1f1f8e20e4e2ecab8f33cbd595
XML generation date: 2024-12-03 14:52:11.257
Product last modified at: 2025-01-01T09:06:04.856Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

LAMTOR4/C7orf59 (D6A4V) Rabbit mAb #12284

Filter:
  • WB
  • IP
  • IF
Western Blotting Image 1: LAMTOR4/C7orf59 (D6A4V) Rabbit mAb
Western blot analysis of extracts from various cell lines using LAMTOR4/C7orf59 (D6A4V) Rabbit mAb.

To Purchase # 12284

Cat. #

Size

12284T
20 µl
12284S
100 µl

Supporting Data

REACTIVITY H M R Mk
SENSITIVITY Endogenous
MW (kDa) 11
Source/Isotype Rabbit IgG
Application Key:
  • WB-Western Blotting 
  • IP-Immunoprecipitation 
  • IF-Immunofluorescence 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Mk-Monkey 

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000
Immunoprecipitation 1:50
Immunofluorescence (Immunocytochemistry) 1:800

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

LAMTOR4/C7orf59 (D6A4V) Rabbit mAb recognizes endogenous levels of total LAMTOR4/C7orf59 protein.

Species Reactivity:

Human, Mouse, Rat, Monkey

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human LAMTOR4/C7orf59 protein.

Background

Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4 (LAMTOR4) is an essential component of the ragulator protein complex that is encoded by the C7orf59 gene (1). The ragulator complex also includes LAMTOR1/C11orf59, LAMTOR2/ROBLD3, LAMTOR3/MAPKSP1, and HBXIP (1,2). This pentameric protein complex localizes to the lysosomal membrane and is essential for the lysosomal localization of Rag GTPases and mTORC1 as well as the subsequent activation of mTORC1 in response to amino acid signaling (1-3).
For Research Use Only. Not For Use In Diagnostic Procedures.
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