FAM3C (D1S2D) XP® Rabbit mAb #15171
- WB
- IHC
- IF
- F
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 25 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IHC-Immunohistochemistry
- IF-Immunofluorescence
- F-Flow Cytometry
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunohistochemistry (Paraffin) | 1:300 |
| Immunofluorescence (Immunocytochemistry) | 1:400 |
| Flow Cytometry (Fixed/Permeabilized) | 1:200 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
FAM3C has also been linked to regulation of osteoblast differentiation (6), and to accumulation of amyloid beta plaques in Alzheimer’s disease (7). FAM3C exists in monomeric and in homodimeric form, and research shows that FAM3C homodimers contain its EMT-inducing and tumor promoting activity (8).
- Waerner, T. et al. (2006) Cancer Cell 10, 227-39.
- Lahsnig, C. et al. (2009) Oncogene 28, 638-50.
- Gao, Z.H. et al. (2014) Histopathology 65, 527-38.
- Chaudhury, A. et al. (2010) Nat Cell Biol 12, 286-93.
- Song, Q. et al. (2014) Tumour Biol 35, 1377-82.
- Bendre, A. et al. Differentiation 93, 50-57.
- Liu, L. et al. (2016) Neuroscience 330, 236-46.
- Kral, M. et al. (2017) FEBS J 284, 3484-3505.
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