Render Target: STATIC
Render Timestamp: 2025-01-22T14:35:18.657Z
Commit: da7e4f2f0d1aed1f1f8e20e4e2ecab8f33cbd595
XML generation date: 2025-01-08 14:01:24.106
Product last modified at: 2025-01-09T08:01:39.190Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

BHLHE40/DEC1 (E6T3E) Rabbit mAb #45723

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H M
    SENSITIVITY Endogenous
    MW (kDa) 46
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:200

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    BHLHE40/DEC1 (E6T3E) Rabbit mAb recognizes endogenous levels of total DEC1 protein.

    Species Reactivity:

    Human, Mouse

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human DEC1 protein.

    Background

    DEC1 (BHLHB2, BHLHE40) is a helix-loop-helix (bHLH) transcription factor that plays a role in the circadian system, or mammalian molecular clock (1-6). Its expression is elevated in response to various stimuli such as light pulses, growth factors, or hypoxia. DEC1 is involved in the homeostasis of regulatory T cells and the cellular differentiation, proliferation, and apoptosis of various cancers (4-6).
    For Research Use Only. Not For Use In Diagnostic Procedures.
    Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
    KARPAS cell line source: Dr. Abraham Karpas at the University of Cambridge.
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