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Commit: c91f970ca8df4f527662a05c7bd6e4d03c6fa173
XML generation date: 2025-03-07 13:11:56.214
Product last modified at: 2025-04-02T14:45:15.934Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

ALKBH3 (E6S4R) Rabbit mAb #87620

Filter:
  • WB
Western Blotting Image 1: ALKBH3 (E6S4R) Rabbit mAb
Western blot analysis of extracts from A549 and PC-3 cells, mock transfected (-) or transfected with ALKBH3 siRNA (+), using ALKBH3 (E6S4R) Rabbit mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower).

To Purchase # 87620

Cat. # Size Qty. Price
87620T 20 µl
$153
87620S 100 µl
$339

Supporting Data

REACTIVITY H M R
SENSITIVITY Endogenous
MW (kDa) 35
Source/Isotype Rabbit IgG
Application Key:
  • WB-Western Blotting 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

ALKBH3 (E6S4R) Rabbit mAb recognizes endogenous levels of total ALKBH3 protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val10 of human ALKBH3 protein.

Background

ALKBH3, also known as Prostate Cancer Antigen-1 (PCA-1), is a DNA and RNA demethylase involved in the repair of alkylated DNA. The protein is overexpressed in prostate cancer and has been linked to other cancer types, including non-small cell lung cancer, renal cell carcinoma, and pancreatic carcinoma (1-3). ALKBH3/PCA-1 is also a potential therapeutic target in prostate cancer (4).
For Research Use Only. Not For Use In Diagnostic Procedures.
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