Render Target: STATIC
Render Timestamp: 2024-11-21T13:05:53.272Z
Commit: 5c4accf06eb7154018ba3f54329c7590f97f534a
XML generation date: 2024-09-20 06:23:20.189
Product last modified at: 2024-09-09T11:45:09.114Z
1% for the planet logo
PDP - Template Name: Growth Factors and Cytokines
PDP - Template ID: *******9ad1159

Human FGF-10 Recombinant Protein #89422

    Product Information

    Storage

    Human FGF-10 Recombinant Protein is supplied as lyophilized material that is very stable at -20°C. It is recommended to reconstitute with sterile water at a concentration of 0.1 mg/mL which can be further diluted in aqueous solutions as needed. Addition of a carrier protein (0.1% HSA or BSA) is recommended for long-term storage.

    Once in solution, store at 4°C and use within 1 month, or store at -20ºC to -80ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles if storing reconstituted material at -20ºC to -80ºC.

    Product Description

    MW (kDa) 19.3
    Purity A greater than or equal to 95% purity was determined by SDS-PAGE.
    Endotoxin Endotoxin levels are less than or equal to 1 EU / 1 μg hFGF-10.
    Activity The bioactivity of recombinant hFGF-10 was determined in a 4MBr-5 cell proliferation assay. The ED50 of each lot is less than or equal to 200 ng/mL.

    Source / Purification

    Recombinant human FGF-10 was expressed in E. coli and is supplied in a lyophilized form.

    Background

    FGF-10 is a member of the large and diverse fibroblast growth factor (FGF) family of peptide growth factors. FGF-10 functions as a signaling molecule that is involved in many important processes (1,2). It binds to receptor FGFR2b and is essential as a signaling growth factor for mesenchymal-to-epithelial transition (3). FGF-10 is involved in limb development and morphogenesis of multiple organs, such as lung, skin, ear, and salivary gland (3,4). Knockout mice for FGF-10 show severe phenotypes with complete truncation of the fore- and hindlimbs and they die shortly after birth due to impaired lung development (4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
    Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
    All other trademarks are the property of their respective owners. Visit our Trademark Information page.