Actinomycin D #15021
Product Information
Product Usage Information
Actinoymcin D is supplied as a lyophilized powder. For a 10 mM stock, reconstitute the 5 mg in 398.28 μl DMSO. Working concentrations and length of treatment can vary depending on the desired effect, but it is typically used at 10-1,000 nM for 6-48 hr.
Storage
Product Description
| Molecular Weight | 1255.4 g/mol |
| Purity | >98% |
| Molecular Formula | C62H86N12O16 |
| CAS | 50-76-0 |
| Solubility | Soluble in DMSO at 50mg/ml. |
Background
- Koba, M. and Konopa, J. (2005) Postepy Hig Med Dosw (Online) 59, 290-8.
- Bensaude, O. (2011) Transcription 2, 103-108.
- Lo, Y.S. et al. (2013) Nucleic Acids Res 41, 4284-94.
- Sobell, H.M. (1985) Proc Natl Acad Sci U S A 82, 5328-31.
- Trask, D.K. and Muller, M.T. (1988) Proc Natl Acad Sci U S A 85, 1417-21.
- Chang, D. et al. (1999) Cell Growth Differ 10, 155-62.
- Khan, Q.A. and Dipple, A. (2000) Carcinogenesis 21, 1611-8.
- Fraschini, A. et al. (2005) Histol Histopathol 20, 107-17.
- Chen, C.S. et al. (2014) Oncotarget 5, 693-703.
Limited Uses
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