Losartan (potassium salt) #59489
Product Information
Product Usage Information
Losartan (potassium salt) is supplied as a lyophilized powder. For a 10 mM stock, reconstitute 5 mg of powder in 1.08 ml of DMSO. Working concentrations and length of treatment can vary depending on the desired effect.
Storage
Product Description
| Molecular Weight | 461 g/mol |
| Purity | >99% |
| Molecular Formula | C22H22ClN6O • K |
| CAS | 124750-99-8 |
| Solubility | Soluble in DMSO at 45 mg/ml or water at 45 mg/ml. |
Background
Losartan (potassium salt) is a known angiotensin II receptor antagonist by selectively and competitively blocking the binding of the angiotensin II hormone (1). In clinical settings, it is useful as an antihypertensive agent and also displays neuroprotective effects against chronic fatigue stress (2,3). Losartan (potassium salt) inhibits collagen I synthesis and induces sirtuin 1 (SirT1) expression and activity (4,5).
Limited Uses
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