PDBu (Phorbol 12,13-Dibutyrate) #12808
Product Information
Product Usage Information
PDBu is supplied as a lyophilized powder. For a 2 mM stock, reconstitute the 1 mg in 990.9 µl DMSO. Working concentrations and length of treatment can vary depending on the desired effect, but it is typically used at 20-2000 nM for 15-30 min. Soluble in DMSO or ethanol.
Storage
Product Description
| Molecular Weight | 504.61 g/mol |
| Purity | >99% |
| Molecular Formula | C28H40O8 |
| CAS | 37558-16-0 |
| Solubility | Souble in DMSO at 25mg/ml and EtOH at 20mg/ml. |
Background
- Blumberg, P.M. et al. (1983) Ann N Y Acad Sci 407, 303-15.
- Driedger, P.E. and Blumberg, P.M. (1980) Proc Natl Acad Sci U S A 77, 567-71.
- Caunt, C.J. and McArdle, C.A. (2010) J Cell Sci 123, 4310-20.
- Bapat, S. et al. (2001) FEBS Lett 499, 21-6.
- Tanabe, A. et al. (2012) J Cell Physiol 227, 618-29.
- Shoyab, M. and Todaro, G.J. (1980) Nature 288, 451-5.
- Chida, K. and Kuroki, T. (1983) Cancer Res 43, 3638-42.
- Dunphy, W.G. et al. (1981) Cancer Res 41, 2640-7.
Limited Uses
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