TPA (12-O-Tetradecanoylphorbol-13-Acetate) #4174
Product Information
Product Usage Information
TPA is supplied as a 1 mg powder. Store at -20C. Before use, dissolve powder in 1 ml DMSO to yield a 1.6 mM stock solution. For working concentration of 200 μM, add 125 μl stock solution to 875 μl DMSO. Treat cells with 200 nM TPA for 20-30 minutes.
TPA is soluble in DMSO and ethanol.
Storage
Product Description
| Molecular Weight | 616.83 g/mol |
| Purity | >99.5% |
| Molecular Formula | C36H56O8 |
| CAS | 16561-29-8 |
| Solubility | Soluble in DMSO and EtOH at 25mg/ml. |
Background
- Rebois, R.V. and Patel, J. (1985) J Biol Chem 260, 8026-31.
- Blumberg, P.M. (1980) Crit Rev Toxicol 8, 153-97.
- Fürstenberger, G. et al. (1981) Proc Natl Acad Sci U S A 78, 7722-6.
- Han, Z.T. et al. (1998) Proc Natl Acad Sci U S A 95, 5357-61.
- Lee, H.W. et al. (2002) J Biol Chem 277, 32624-31.
- Han, Z.T. et al. (1998) Proc Natl Acad Sci U S A 95, 5362-5.
Limited Uses
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