Z-VAD(OMe)-FMK #60332
Product Information
Product Usage Information
Z-VAD(OMe)-FMK is supplied as a lyophilized powder. For a 10 mM stock, reconstitute the 1 mg of powder in 213.9 μl of DMSO. Working concentrations and length of treatment can vary depending on the desired effect, but it is typically used as a pre-treatment at 5-100 μM for 1 hr.
Storage
Product Description
| Molecular Weight | 467.5 g/mol |
| Purity | >95% |
| Molecular Formula | C22H30FN3O7 |
| CAS | 187389-52-2 |
| Solubility | Soluble in DMSO at 5mg/ml. |
Background
- Garcia-Calvo, M. et al. (1998) J Biol Chem 273, 32608-13.
- Lawrence, C.P. and Chow, S.C. (2012) Toxicol Appl Pharmacol 265, 103-12.
- Caserta, T.M. et al. (2003) Apoptosis 8, 345-52.
- Van Noorden, C.J. (2001) Acta Histochem 103, 241-51.
- Slee, E.A. et al. (1996) Biochem J 315 ( Pt 1), 21-4.
- Schotte, P. et al. (1999) FEBS Lett 442, 117-21.
- Misaghi, S. et al. (2006) Cell Death Differ 13, 163-5.
- Deszcz, L. et al. (2004) FEBS Lett 560, 51-5.
- Alam, A. et al. (1999) J Exp Med 190, 1879-90.
- Boissonnas, A. et al. (2002) Eur J Immunol 32, 3007-15.
Limited Uses
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