Render Target: STATIC
Render Timestamp: 2024-11-21T13:30:37.444Z
Commit: 5c4accf06eb7154018ba3f54329c7590f97f534a
XML generation date: 2024-04-05 20:22:12.250
Product last modified at: 2024-06-27T13:36:12.801Z
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PDP - Template Name: Blocking Peptide
PDP - Template ID: *******6db2f4c

EGR1 Blocking Peptide #1015

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    Product Information

    Product Usage Information

    Use as a blocking reagent to evaluate the specificity of antibody reactivity in dot blot protocols.

    Storage

    Supplied in 20 mM potassium phosphate (pH 7.0), 50 mM NaCl, 0.1 mM EDTA, 1 mg/ml BSA and 5% glycerol. 15 DMSO. Store at –20°C.

    Product Description

    This peptide is used to block EGR1 rabbit poly #4152, (15F7) Rabbit mAb #4153, and (44D5) Rabbit mAb #4154 reactivity.

    Quality Control

    The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry. The peptide blocks EGR1 (15F7) Rabbit mAb #4153 by dot blot.

    Background

    EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (ER) to regulate target gene expression (1). The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1,2). Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2,3).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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