4E-BP Antibody Sampler Kit #9955
Product Information
Kit Usage Information
Protocols
- 2845: Western Blotting, Immunoprecipitation (Magnetic), Immunohistochemistry (Paraffin)
- 2855: Western Blotting, Immunohistochemistry (Paraffin), Immunofluorescence, Flow
- 4923: Western Blotting, Immunofluorescence, Flow
- 7074: Western Blotting
- 9451: Western Blotting, Immunoprecipitation (Agarose)
- 9455: Western Blotting, Immunoprecipitation (Agarose)
- 9644: Western Blotting, Immunoprecipitation (Agarose), Immunohistochemistry (Paraffin), Immunofluorescence, Flow
Product Description
Specificity / Sensitivity
Source / Purification
Background
4E-BP2 and 4E-BP3 share high sequence homology with 4E-BP1, including conservation of the major FRAP/mTOR-dependent phosphorylation sites. Preliminary data suggests that phosphorylation of 4E-BP2 is regulated in a similar manner to that of 4E-BP1, although phosphorylation of this protein has not been as extensively studied (6).
- Pause, A. et al. (1994) Nature 371, 762-7.
- Brunn, G.J. et al. (1997) Science 277, 99-101.
- Gingras, A.C. et al. (1998) Genes Dev 12, 502-13.
- Fadden, P. et al. (1997) J Biol Chem 272, 10240-7.
- Gingras, A.C. et al. (1999) Genes Dev 13, 1422-37.
- Lin, T.A. and Lawrence, J.C. (1996) J. Biol. Chem. 271, 30199-30204.
Limited Uses
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