Acetyl-α-Tubulin (Lys40) (6-11B-1) Mouse mAb #12152
We recommend the following alternatives
#
Product Name
- WB
- IP
- IF
Inquiry Info. # 12152
Please see our recommended alternatives.
Supporting Data
| REACTIVITY | H R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 52 |
| Source/Isotype | Mouse IgG2b |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
| Immunofluorescence (Frozen) | 1:800 |
| Immunofluorescence (Immunocytochemistry) | 1:800 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
The Elongator complex catalytic subunit (Elp3) acetylates α-tubulin at Lys40, while the histone deacetylase HDAC6 functions as a tubulin deacetylase. This post-translational modification may be required for dynamic cell shape remodeling, cell motility, tubulin stability, and terminal branching of cortical neurons (2,3).
Limited Uses
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