APC10 Antibody #14807
- WB
Supporting Data
| REACTIVITY | H M R Mk |
| SENSITIVITY | Endogenous |
| MW (kDa) | 24 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
- Mk-Monkey
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
Anaphase-promoting complex subunit 10 (APC10, DOC1) is a highly conserved, core component of the anaphase promoting complex/cyclosome (10,11). Research studies indicate that APC10 participates in substrate recognition by the APC/C (3,12,13).
- Qiao, X. et al. (2010) Cell Cycle 9, 3904-12.
- Harper, J.W. et al. (2002) Genes Dev 16, 2179-206.
- Chang, L. et al. (2014) Nature 513, 388-93.
- Carroll, C.W. and Morgan, D.O. (2002) Nat Cell Biol 4, 880-7.
- Gmachl, M. et al. (2000) Proc Natl Acad Sci U S A 97, 8973-8.
- Leverson, J.D. et al. (2000) Mol Biol Cell 11, 2315-25.
- Kraft, C. et al. (2005) Mol Cell 18, 543-53.
- Glotzer, M. et al. (1991) Nature 349, 132-8.
- Pfleger, C.M. and Kirschner, M.W. (2000) Genes Dev 14, 655-65.
- Kurasawa, Y. and Todokoro, K. (1999) Oncogene 18, 5131-7.
- Grossberger, R. et al. (1999) J Biol Chem 274, 14500-7.
- Carroll, C.W. et al. (2005) Curr Biol 15, 11-8.
- Passmore, L.A. et al. (2003) EMBO J 22, 786-96.
Limited Uses
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