ApoA4 (1D6B6) Mouse mAb #5700
- WB
- IP
Supporting Data
| REACTIVITY | H M R Mk |
| SENSITIVITY | Endogenous |
| MW (kDa) | 45 |
| Source/Isotype | Mouse IgG2a |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
- Mk-Monkey
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Apolipoprotein A-IV (ApoA4) is a glycoprotein that exists as a free apolipoprotein in human plasma (3,4). ApoA4 activates the lecithin cholesterol acyl transferase (5-7) to modulate the rate of lipid transfer protein (LTP) activity (7). Additional evidence suggests that ApoA4 may also act as an antioxidant to inhibit LDL oxidation in the atherosclerosis model (8).
- Kwiterovich, P.O. (2000) Am J Cardiol 86, 5L-10L.
- Hussain, M.M. (2000) Atherosclerosis 148, 1-15.
- Utermann, G. and Beisiegel, U. (1979) Eur J Biochem 99, 333-43.
- Hayashi, H. et al. (1990) J Lipid Res 31, 1613-25.
- Steinmetz, A. and Utermann, G. (1985) J Biol Chem 260, 2258-64.
- Chen, C.H. and Albers, J.J. (1985) Biochim Biophys Acta 836, 279-85.
- Main, L.A. et al. (1996) Biochim Biophys Acta 1300, 17-24.
- Wong, W.M. et al. (2007) Atherosclerosis 192, 266-74.
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