CAP1 (D2K3J) Rabbit mAb #47055
- WB
Supporting Data
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 56 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val337 of human CAP1 protein.
Background
Adenylyl cyclase-associated protein 1 (CAP1) is a widely expressed actin regulatory protein that plays a role in adhesion through its interactions with talin1 and FAK (1). High CAP1 expression is associated with metastasis in hepatocellular carcinoma (2), and esophageal squamous cell carcinoma (3). Research studies also show that CAP1 expression in human epithelial ovarian cancer correlates with proliferation, histological grade, and prognosis (4).
Limited Uses
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