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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

DIMT1 Antibody #31358

Filter:
  • WB
Western Blotting Image 1: DIMT1 Antibody
Western blot analysis of extracts from various cell lines using DIMT1 Antibody (upper) and β-Actin (D6A8) Rabbit mAb #8457 (lower).

To Purchase # 31358

Cat. # Size Qty. Price Ships
31358S 100 µl
$306 Jan 23

Supporting Data

REACTIVITY H M R Mk
SENSITIVITY Endogenous
MW (kDa) 35
SOURCE Rabbit
Application Key:
  • WB-Western Blotting 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Mk-Monkey 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

DIMT1 Antibody recognizes endogenous levels of total DIMT1 protein.

Species Reactivity:

Human, Mouse, Rat, Monkey

Source / Purification

Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val98 of human DIMT1 protein. Antibodies are purified by peptide affinity chromatography.

Background

Dimethyladenosine transferase 1 (DIMT1), also known as DIMT1L, is a methyltransferase responsible for the dimethylation of adenosines on the 18S rRNA subunit. Binding of DIMT1 to the pre-rRNA is required for proper processing of the 18S subunit (1). Independent of its catalytic activity, DIMT1 seems to function as a scaffold protein that is essential for the assembly of the 40S rRNA subunit (2). DIMT1 also has been shown to have higher expression in certain cancer types, including multiple myeloma and gastric cancer (3,4).
For Research Use Only. Not For Use In Diagnostic Procedures.
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