EXOC7 (E4W6R) Rabbit mAb #28666
- WB
- IP
Supporting Data
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 75-80 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:100 |
Storage
Protocol
Specificity / Sensitivity
EXOC7 (E4W6R) Rabbit mAb recognizes endogenous levels of total EXOC7 protein. This antibody is expected to detect all isoforms of EXOC7. By western blot, this antibody detects a band of approximately 140 kDa of unknown origin in MCF7 cells.
Species Reactivity:
Human, Mouse, Rat
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg72 of human EXOC7 protein.
Background
EXOC7/Exo70 is a component of the exocyst complex, which regulates the docking of exocytic vesicles to the plasma membrane and the release of cargo, including neurotransmitters, hormones, and membrane proteins (1). EXOC7 plays a role in cell motility, migration, and invasion, and is an independent prognostic factor in colon cancer (2).
Limited Uses
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