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Product last modified at: 2025-04-01T08:00:16.526Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

Glut5 (F4A5K) Rabbit mAb #71407

Filter:
  • WB
Western Blotting Image 1: Glut5 (F4A5K) Rabbit mAb
Western blot analysis of extracts from various cell lines using Glut5 (F4A5K) Rabbit mAb (upper) or GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). Negative expression of Glut5 protein in T-47D and OVCAR-8 cells is consistent with the predicted expression pattern.

To Purchase # 71407

Cat. # Size Qty. Price
71407T 20 µl
$155
71407S 100 µl
$371

Supporting Data

REACTIVITY H
SENSITIVITY Endogenous
MW (kDa) 42-80
Source/Isotype Rabbit IgG
Application Key:
  • WB-Western Blotting 
Species Cross-Reactivity Key:
  • H-Human 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000
Simple Western™ 1:10 - 1:50

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

Glut5 (F4A5K) Rabbit mAb recognizes endogenous levels of total Glut5 protein. This antibody does not cross-react with Glut1, Glut2, Glut3, or Glut4 protein.

Species Reactivity:

Human

Source / Purification

Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human Glut5 protein.

Background

Glucose transporter 5 (Glut5, also known as SLC2A5) functions as a fructose transporter. Glut5 transports fructose into epithelial cells of small intestine (1,2). Besides the small intestine, Glut5 is also expressed in other tissues, such as skeletal muscle and the prostate gland (3). In addition, studies show that Glut5 expression is significantly upregulated in prostate cancer, and fructose promotes prostate cancer growth (2). Furthermore, fructose metabolism mediated by Glut5 in tumor endothelial cells from hepatocellular carcinoma (HCC) enhances tumor angiogenesis by boosting respiration in mitochondria (4).

Pathways

Explore pathways related to this product.


For Research Use Only. Not For Use In Diagnostic Procedures.
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