Render Target: STATIC
Render Timestamp: 2024-12-27T11:31:24.364Z
Commit: f2d32940205a64f990b886d724ccee2c9935daff
XML generation date: 2024-08-01 15:28:46.363
Product last modified at: 2024-12-17T12:45:14.443Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

IFI6 Antibody #54355

Filter:
  • WB

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 12
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    IFI6 Antibody recognizes endogenous levels of total IFI6 protein. This antibody does not cross-react with other ISG12 family proteins.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human IFI6 protein. Antibodies are purified by peptide affinity chromatography.

    Background

    Interferon alpha-inducible protein 6 (IFI6) belongs to the ISG12 family of proteins and is a small, multipass transmembrane protein localized to mitochondrial membranes (1,2). IFI6 is one of the first interferon-stimulated genes to be identified and research studies have shown that IFI6 regulates apoptotic signaling pathways triggered in response to type-I interferons (3,4). In addition, IFI6 participates in type-I interferon-mediated antiviral signaling by mitigating viral replication (5,6).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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