MELK Antibody #2274
- WB
- IP
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 74 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Finally, recent studies on human tumor samples and cell lines suggest that MELK expression is frequently elevated in cancer relative to normal tissues (11). MELK may provide a growth advantage for neoplastic cells, and may be a potential target for anti-cancer therapies.
- Heyer, B.S. et al. (1999) Dev. Dyn. 215, 344-51.
- Davezac, N. et al. (2002) Oncogene 21, 7630-41.
- Vulsteke, V. et al. (2004) J. Biol. Chem. 279, 8642-7.
- Nakano, I. et al. (2005) J. Cell Biol. 170, 413-27.
- Tassan, J.P. and Le Goff, X. (2004) Biol. Cell 96, 193-9.
- Woods, A. et al. (2003) Curr. Biol. 13, 2004-8.
- Lizcano, J.M. et al. (2004) EMBO J. 23, 833-43.
- Beullens, M. et al. (2005) J. Biol. Chem. 280, 40003-11.
- Badouel, C. et al. (2006) Cell Cycle. 5, 883-889.
- Seong, H.A. et al. (2002) Biochem. J. 361, 597-604.
- Gray, D. et al. (2005) Cancer Res. 65, 9751-61.
Limited Uses
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