Mouse Reactive Necroptosis Antibody Sampler Kit #47928
Product Information
Kit Usage Information
Protocols
- 3493: Western Blotting, Immunoprecipitation (Agarose), Immunofluorescence, Flow
- 7074: Western Blotting
- 15828: Western Blotting, Immunoprecipitation (Agarose)
- 37333: Western Blotting, Immunofluorescence
- 37705: Western Blotting, Immunoprecipitation (Agarose)
- 53286: Western Blotting, Immunoprecipitation (Agarose)
- 91702: Western Blotting, Immunofluorescence
Product Description
Specificity / Sensitivity
Source / Purification
Background
In mice, activation of RIP3 is associated with phosphorylation at Thr231 and Ser232 (11), and then MLKL is phosphorylated at Ser345 by RIP3 (12).
- Christofferson, D.E. and Yuan, J. (2010) Curr Opin Cell Biol 22, 263-8.
- Kaczmarek, A. et al. (2013) Immunity 38, 209-23.
- Zhou, W. and Yuan, J. (2014) Semin Cell Dev Biol 35, 14-23.
- Degterev, A. et al. (2008) Nat Chem Biol 4, 313-21.
- Ofengeim, D. and Yuan, J. (2013) Nat Rev Mol Cell Biol 14, 727-36.
- Sun, L. et al. (2012) Cell 148, 213-27.
- Cai, Z. et al. (2014) Nat Cell Biol 16, 55-65.
- Chen, X. et al. (2014) Cell Res 24, 105-21.
- Wang, H. et al. (2014) Mol Cell 54, 133-46.
- Dondelinger, Y. et al. (2014) Cell Rep 7, 971-81.
- Chen, W. et al. (2013) J Biol Chem 288, 16247-61.
- Murphy, J.M. et al. (2013) Immunity 39, 443-53.
Limited Uses
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