Mouse Reactive Senescence Marker Antibody Sampler Kit #78551
Product Information
Kit Usage Information
Protocols
- 6893: Western Blotting, Immunohistochemistry (Paraffin)
- 7074: Western Blotting
- 9718: Western Blotting, Immunohistochemistry (Leica® Bond™), Immunohistochemistry (Paraffin), Immunofluorescence*, Flow Cytometry, BSA-free Methanol Permeabilization Protocol
- 11948: Western Blotting, Immunoprecipitation (Agarose), Immunofluorescence, Flow
- 12912: Western Blotting, Immunoprecipitation (Magnetic), Immunofluorescence, Flow
- 17416: Western Blotting, Immunohistochemistry (Paraffin)
- 29271: Western Blotting, Immunoprecipitation (Magnetic)
- 37543: Western Blotting, Immunoprecipitation (Magnetic)
- 87809: Western Blotting, Immunoprecipitation (Agarose)
Product Description
Specificity / Sensitivity
Source / Purification
Background
Because there is no single biomarker that can be used to definitively identify senescent cells, researchers must rely on a collection of biomarkers commonly associated with senescence (3). The Mouse Reactive Senescence Marker Antibody Sampler Kit provides a collection of antibodies to commonly used biomarkers of senescence-associated cell cycle arrest (p16 INK4A, p21 Waf1/Cip1), senescence-associated DNA damage (gamma-Histone H2A.X), and the SASP (HMGB1, IL-6, TNF-α, MMP2). The kit also includes an antibody to lamin B1, which is frequently reduced in senescent cells.
Limited Uses
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