MRP3/ABCC3 (D8V8J) Rabbit mAb #39909
- WB
- IP
Supporting Data
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 160-220 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Elevated expression of MRP3 has been detected in various cancer types such as hepatocellular carcinomas, primary ovarian cancer, and adult acute lymphoblastic leukemia (ALL) (9-11). Overexpression of MRP3 was reported to be a prognostic factor in ALL and adult acute myeloid leukemia (AML) (11,12).
- Uchiumi, T. et al. (1998) Biochem Biophys Res Commun 252, 103-10.
- Scheffer, G.L. et al. (2002) Lab Invest 82, 193-201.
- Kiuchi, Y. et al. (1998) FEBS Lett 433, 149-52.
- König, J. et al. (1999) Hepatology 29, 1156-63.
- Zelcer, N. et al. (2001) J Biol Chem 276, 46400-7.
- Belinsky, M.G. et al. (2005) Mol Pharmacol 68, 160-8.
- Dickerson, W.G. (1992) Dent Today 11, 54-5.
- Soroka, C.J. et al. (2001) Hepatology 33, 783-91.
- Nies, A.T. et al. (2001) Int J Cancer 94, 492-9.
- Ohishi, Y. et al. (2002) Clin Cancer Res 8, 3767-75.
- Plasschaert, S.L. et al. (2005) Clin Cancer Res 11, 8661-8.
- Benderra, Z. et al. (2005) Clin Cancer Res 11, 7764-72.
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