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Commit: c91f970ca8df4f527662a05c7bd6e4d03c6fa173
XML generation date: 2025-03-07 13:16:20.248
Product last modified at: 2025-03-10T11:15:09.786Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

MSR1 (E7P6W) Rabbit mAb #98215

Filter:
  • IHC
Immunohistochemistry Image 1: MSR1 (E7P6W) Rabbit mAb
Immunohistochemical analysis of paraffin-embedded 4T1 syngeneic tumor using MSR1 (E7P6W) Rabbit mAb.

To Purchase # 98215

Cat. # Size Qty. Price
98215T 20 µl
$162
98215S 100 µl
$357

Supporting Data

REACTIVITY M
SENSITIVITY Endogenous
MW (kDa)
Source/Isotype Rabbit IgG
Application Key:
  • IHC-Immunohistochemistry 
Species Cross-Reactivity Key:
  • M-Mouse 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Immunohistochemistry (Paraffin) 1:150 - 1:600

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

MSR1 (E7P6W) Rabbit mAb recognizes endogenous levels of total MSR1 protein. Non-specific staining was observed in mouse testis and pancreatic islets by immunohistochemistry.

Species Reactivity:

Mouse

Source / Purification

Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of mouse MSR1 protein.

Background

Macrophage Scavenger receptor types I and II (MSR1, also known as SCARA1) are members of the class A macrophage scavenger receptor family. These proteins bind large quantities of modified lipoproteins and promote endocytosis. Upregulation of MSR1 in infiltrating myeloid cells may mediate clearance of specific damage signals in response to tissue injury, including ischemic stroke (1). MSR1 germline mutations are also associated with increased prostate cancer susceptibility in some patient cohorts (2). MSR1 is observed to be upregulated in differentiated THP-1 cells (3).
For Research Use Only. Not For Use In Diagnostic Procedures.
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