Name: MT-ATP6 Antibody
Price: 302.00 USD
Availability: InStock

Filter:

WB
IP

Supporting Data

REACTIVITY	H M R
SENSITIVITY	Endogenous
MW (kDa)	20
SOURCE	Rabbit

Application Key:

WB-Western Blotting
IP-Immunoprecipitation

Species Cross-Reactivity Key:

H-Human
M-Mouse
R-Rat

Product Information

Product Usage Information

Application	Dilution
Western Blotting	1:1000
Immunoprecipitation	1:50

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

MT-ATP6 Antibody recognizes endogenous levels of total MT-ATP6 protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Polyclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MT-ATP6 protein. Antibodies are purified by peptide affinity chromatography.

Background

Mitochondrially-encoded ATP Synthase Membrane Subunit 6 (MT-ATP6) is a product of MT-ATP6, one of 13 protein-encoding genes in the mitochondrial genome. MT-ATP6 comprises one subunit of the transmembrane F₁F_O ATP synthase (Complex V), which catalyzes the final step of oxidative phosphorylation in the electron transport chain (1). Numerous mutations in the MT-ATP6 gene have been identified that lead to defects in oxidative phosphorylation. Many of these are strongly associated with distinct disease states, including Leigh syndrome (2) and Charcot-Marie-Tooth (CMT) disease (3).

Database Links

UniProt ID: P00846

Entrez-Gene Id: 4508

Limited Uses

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For Research Use Only. Not For Use In Diagnostic Procedures.

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MT-ATP6 Antibody #70262