Render Target: STATIC
Render Timestamp: 2025-01-07T09:42:54.095Z
Commit: 199712eb9daea12d88cc0e67894a8a09f475f8cb
XML generation date: 2024-09-30 01:59:22.059
Product last modified at: 2025-01-01T09:02:46.538Z
Cell Signaling Technology Logo

Basket Updated

0

Items added

1% for the planet logo
PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77

Parkin (E6B1P) Mouse mAb #62960

Filter:
  • WB
Western Blotting Image 1: Parkin (E6B1P) Mouse mAb
Western blot analysis of extracts from various tissues and cell lines using Parkin (E6B1P) Mouse mAb (upper) or β-Actin (D6A8) Rabbit mAb #8457 (lower). Negative expression of Parkin protein in 22Rv1 cells is consistent with the predicted expression pattern.

To Purchase # 62960

Cat. # Size Qty. Price
62960T 20 µl
$152
62960S 100 µl
$336

Supporting Data

REACTIVITY H M R
SENSITIVITY Endogenous
MW (kDa) 50
Source/Isotype Mouse IgG2a kappa
Application Key:
  • WB-Western Blotting 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 
  • Related Products

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000
Simple Western™ 1:10 - 1:50

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

Parkin (E6B1P) Mouse mAb recognizes endogenous levels of total Parkin protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human Parkin protein.

Background

Parkin is a protein of 465 amino acids with an amino-terminal ubiquitin domain and a carboxy-terminal RING-box (1). In the case of autosomal recessive juvenile Parkinsonism (AR-JP), deletions have been found in the gene on chromosome 6 encoding the protein Parkin (2).

Pathways

Explore pathways related to this product.


For Research Use Only. Not For Use In Diagnostic Procedures.
Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
All other trademarks are the property of their respective owners. Visit our Trademark Information page.