Render Target: STATIC
Render Timestamp: 2024-12-20T11:32:31.778Z
Commit: f2d32940205a64f990b886d724ccee2c9935daff
XML generation date: 2024-08-01 15:28:53.504
Product last modified at: 2024-12-12T12:30:09.530Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

Perilipin-2 Antibody #45535

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 52
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Perilipin-2 Antibody recognizes endogenous levels of total perilipin-2 protein. This antibody does not cross-react with perilipin-1 protein.

    Species Reactivity:

    Human

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human perilipin-2 protein. Antibodies are purified by peptide affinity chromatography.

    Background

    Eukaryotic cells store lipids in lipid droplets. These intracellular lipid storage structures are covered by members of the perilipin family of lipid droplet coat proteins. Perilipins establish an interface between stored lipids and the cytosol and coordinate lipid storage and utilization (1-3). Mice deficient of perilipin-2 have decreased levels of triglycerides in the liver and are protected from fatty liver disease. In addition, these mice show increased autophagy in the liver. In contrast, overexpression of perilipin-2 protects lipid droplets from autophagy (4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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