Phospho-Axl (Tyr702) (D12B2) Rabbit mAb (BSA and Azide Free) #28451
- WB
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 138 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.
BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
Formulation
For standard formulation of this product see product #5724
Storage
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
Phosphorylation of Axl Receptor on Tyr702 was identified at Cell Signaling Technology (CST) using PhosphoScan®, CST's LC-MS/MS platform for phosphorylation site discovery (5). Phosphorylation of Axl on Tyr702 was also reported in select carcinoma cell lines (6).
- Crosier, K.E. and Crosier, P.S. (1997) Pathology 29, 131-5.
- Demarchi, F. et al. (2001) J Biol Chem 276, 31738-44.
- Lee, W.P. et al. (2002) Oncogene 21, 329-36.
- Bellosta, P. et al. (1997) Oncogene 15, 2387-97.
- Rikova, K. et al. (2007) Cell 131, 1190-203.
- Guo, A. et al. (2008) Proc Natl Acad Sci USA 105, 692-7.
Limited Uses
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