Phospho-Axl (Tyr779) Antibody #96453
- WB
- IP
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 138 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:50 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
Phosphorylation of Axl receptor on Tyr779 is an indication of the receptor activation. The phosphorylation correlates to tumor progression and epithelial-mesenchymal transition (EMT), as well as drug therapy resistance (5-7).
- Crosier, K.E. and Crosier, P.S. (1997) Pathology 29, 131-5.
- Demarchi, F. et al. (2001) J Biol Chem 276, 31738-44.
- Lee, W.P. et al. (2002) Oncogene 21, 329-36.
- Bellosta, P. et al. (1997) Oncogene 15, 2387-97.
- Asiedu, M.K. et al. (2014) Oncogene 33, 1316-24.
- Onken, J. et al. (2017) Oncotarget 8, 50403-50414.
- Niu, X. et al. (2021) Blood 137, 3641-3655.
Limited Uses
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