Phospho-CaMKK2 (Ser495) (E7W9S) Rabbit mAb #35392
- WB
Supporting Data
| REACTIVITY | H M |
| SENSITIVITY | Endogenous |
| MW (kDa) | 68, 70 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
Multiple CaMKK2 phosphorylation sites have been identified, including Ser495, and C-terminal phosphorylation of the CaMKK2 autoinhibitory region may regulate its function and localization (8).
- Tokumitsu, H. et al. (1997) Biochemistry 36, 12823-7.
- Tokumitsu, H. et al. (1995) J Biol Chem 270, 19320-4.
- Anderson, K.A. et al. (1998) J Biol Chem 273, 31880-9.
- Hawley, S.A. et al. (2005) Cell Metab 2, 9-19.
- Peters, M. et al. (2003) J Neurosci 23, 9752-60.
- Lin, F. et al. (2011) Endocrinology 152, 3668-79.
- Schumacher, A.M. et al. (2004) Biochemistry 43, 8116-24.
- Knittle, A.M. et al. (2017) J Biol Chem 292, 19890-19904.
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