Phospho-eNOS (Ser113) Antibody #9575
- WB
Supporting Data
| REACTIVITY | H B |
| SENSITIVITY | Endogenous |
| MW (kDa) | 140 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- B-Bovine
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
eNOS is activated by VEGF, and this activation is associated with dephsophorylation of eNOS at serine 113. Cyclosporin A blocks this dephosphorylation of eNOS upon VEGF stimulation (8).
- Fulton, D. et al. (2001) J Pharmacol Exp Ther 299, 818-24.
- Shaul, P.W. (2002) Annu Rev Physiol 64, 749-74.
- Chen, Z.P. et al. (1999) FEBS Lett 443, 285-9.
- Dimmeler, S. et al. (1999) Nature 399, 601-5.
- Fulton, D. et al. (1999) Nature 399, 597-601.
- Harris, M.B. et al. (2001) J Biol Chem 276, 16587-91.
- Thomas, S.R. et al. (2002) J Biol Chem 277, 6017-24.
- Kou, R. et al. (2002) J Biol. Chem. 277(33) , 29669-29673.
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