Phospho-FAM134B (Ser151) (F8R4D) Rabbit mAb #89678
- WB
- IP
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 70 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:200 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
In response to ER stress, CAMKII phosphorylates FAM134B at Ser151 to facilitate oligomerization, ER membrane fragmentation, and ER-phagy (9).
- Islam, F. et al. (2018) J Cell Physiol 233, 4479-89.
- Khaminets, A. et al. (2015) Nature 522, 354-8.
- Chiramel, A.I. et al. (2016) J Infect Dis 214, S319-25.
- Murphy, S.M. et al. (2012) J Neurol Neurosurg Psychiatry 83, 119-20.
- Kurth, I. et al. (2009) Nat Genet 41, 1179-81.
- Tang, W.K. et al. (2007) Int J Mol Med 19, 915-23.
- Islam, F. et al. (2018) Genes Chromosomes Cancer 57, 240-51.
- Islam, F. et al. (2017) Hum Genet 136, 321-37.
- Jiang, X. et al. (2020) EMBO J 39, e102608.
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