Phospho-SRC-3 (Thr24) Antibody #2979
- WB
- IF
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 160 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunofluorescence (Immunocytochemistry) | 1:200 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Phosphorylation of Thr24 of SRC-3 proteins can be induced by stimulation with EGF. Phosphorylated SRC-3 translocates from the cytoplasm to the nucleus where it interacts with other transcription factors and steroid hormone receptors and regulates gene expression (15).
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- Wu, R.C. et al. (2004) Mol. Cell 15, 937-949.
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- Zhou, H.J. et al. (2005) Cancer Res. 65, 7976-7983.
- Torres-Arzayus, M.I. et al. (2004) Cancer Cell 6, 263-274.
- Wachtel, M. et al. (2004) Cancer Res. 64, 5539-5545.
- Deguchi, K. et al. (2003) Cancer Cell 3, 259-271.
- Amazit, L. et al. (2007) Mol. Cell Biol. 27, 6913-6932.
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