Pim Kinase Antibody Sampler Kit #9779
Product Information
Kit Usage Information
Protocols
- 3247: Western Blotting
- 4165: Western Blotting
- 4730: Western Blotting, Immunoprecipitation (Magnetic)
- 5284: Western Blotting, Immunohistochemistry (Paraffin), Flow
- 7074: Western Blotting
- 9239: Western Blotting
Product Description
Specificity / Sensitivity
Source / Purification
Background
The corresponding pim-1 gene encodes a pair of proteins through use of different translation initiation sites. Both larger 44 kDa (Pim-1L) and smaller 33 kDa (Pim-1S) proteins are active kinases, but differ in stability (13).
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- Dautry, F. et al. (1988) J Biol Chem 263, 17615-20.
- Möröy, T. et al. (1993) Proc Natl Acad Sci USA 90, 10734-8.
- Lilly, M. and Kraft, A. (1997) Cancer Res 57, 5348-55.
- Leverson, J.D. et al. (1998) Mol Cell 2, 417-25.
- Winn, L.M. et al. (2003) Cell Cycle 2, 258-62.
- Pasqualucci, L. et al. (2001) Nature 412, 341-6.
- Kim, O. et al. (2004) Oncogene 23, 1838-44.
- Aho, T.L. et al. (2004) FEBS Lett 571, 43-9.
- Yan, B. et al. (2003) J Biol Chem 278, 45358-67.
- Saris, C.J. et al. (1991) EMBO J 10, 655-64.
Limited Uses
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