Render Target: STATIC
Render Timestamp:
4/1/2025, 6:59:50 AM EDT
4/1/2025, 10:59:50 AM UTC
Commit: 461ca8d8fe5b1efd4c01fc87e5b5eb592e2d154a
XML generation date: 2025-03-18 22:04:20.280
Product last modified at: 2025-03-25T14:15:10.695Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
  1. Products /
  2. Primary Antibodies /
  3. Rad51D (F6U3A) Rabbit mAb
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

Rad51D (F6U3A) Rabbit mAb #39370

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 30
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunoprecipitation 1:100

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    Rad51D (F6U3A) Rabbit mAb recognizes endogenous levels of total Rad51D protein. This antibody detects an approximately 80 kDa protein of unknown identity in some cell lines.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human Rad51D protein.

    Background

    Rad51 paralog D (Rad51D) is one of five Rad51 paralogs that form two distinct complexes, BCDX2 (Rad51B, Rad51C, Rad51D, and XRCC2) and CX3 (Rad51C and XRCC3) (1). Along with Rad51, these complexes are crucial in the repair of DNA double-strand breaks through homologous recombination (2), and in the response to DNA replication stress (3,4). Germline mutations in homologous recombination-associated genes, including those encoding Rad51C and Rad51D, lead to increased susceptibility to breast, ovarian, prostate, and pancreatic cancer (5).

    Database Links

    UniProt ID: O75771


    Entrez-Gene Id: 5892


    Limited Uses

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    For Research Use Only. Not For Use In Diagnostic Procedures.
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