RecQ4 Antibody #2814
- WB
Inquiry Info. # 2814
Please see our recommended alternatives.
Supporting Data
| REACTIVITY | H R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 150 |
| SOURCE | Rabbit |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- R-Rat
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
The antigen sequence used to produce this antibody shares 100% sequence homology with the species listed here, but reactivity has not been tested or confirmed to work by CST. Use of this product with these species is not covered under our Product Performance Guarantee.
Species predicted to react based on 100% sequence homology:
Source / Purification
Background
Mutations in the RECQL4 gene have been identified in a subset of patients with Rothmund-Thomson syndrome (RTS) - a disorder characterized by growth deficiency, skin and skeletal abnormalities, and cancer predisposition. Two more autosomal recessive disorders have been associated with RECQL4 gene mutations: RAPADILINO, and Baller-Gerold syndromes (4).
- Hanada, K. and Hickson, I.D. (2007) Cell Mol Life Sci.
- Macris, M.A. et al. (2006) DNA Repair (Amst) 5, 172-80.
- Yin, J. et al. (2004) Hum Mol Genet 13, 2421-30.
- Dietschy, T. et al. (2007) Cell Mol Life Sci 64, 796-802.
- LeRoy, G. et al. (2005) Nucleic Acids Res 33, 6251-7.
- Sengupta, S. et al. (2005) Oncogene 24, 1738-48.
Limited Uses
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