Render Target: STATIC
Render Timestamp: 2024-12-20T11:59:03.996Z
Commit: f2d32940205a64f990b886d724ccee2c9935daff
XML generation date: 2024-08-01 15:28:00.139
Product last modified at: 2024-12-09T19:30:10.461Z
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PDP - Template Name: Polyclonal Antibody
PDP - Template ID: *******59c6464

RPL10 Antibody #72912

Filter:
  • WB

    Supporting Data

    REACTIVITY H M R Mk
    SENSITIVITY Endogenous
    MW (kDa) 25
    SOURCE Rabbit
    Application Key:
    • WB-Western Blotting 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 
    • Mk-Monkey 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    RPL10 Antibody recognizes endogenous levels of total RPL10 protein.

    Species Reactivity:

    Human, Mouse, Rat, Monkey

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro205 of human RPL10 protein. Antibodies are purified by peptide affinity chromatography.

    Background

    RPL10, also known as QM, is an essential 60S ribosomal subunit protein that helps with the joining of the 40S and 60S subunits (1-3). During ribosome assembly, RPL10 is one of the last proteins to be added that make up the peptide transferase center, and is responsible for the release of nuclear export factor NMD3 (4,5). An R98S mutation in RPL10 has been shown in T-cell acute lymphoblastic leukemia, and additional mutations have been found in autism spectrum disorders (6-8).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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