SAMHD1 (E8V1G) Rabbit mAb #76700
- WB
- IP
- F
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 72 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IP-Immunoprecipitation
- F-Flow Cytometry
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunoprecipitation | 1:200 |
| Flow Cytometry (Fixed/Permeabilized) | 1:200 - 1:800 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Full-length SAMHD1 oligomerizes in a dGTP-dependent manner in vitro, leading to high molecular weight dimers, trimers, or tetramers (7).
- Rice, G.I. et al. (2009) Nat Genet 41, 829-32.
- Laguette, N. et al. (2011) Nature 474, 654-7.
- Hrecka, K. et al. (2011) Nature 474, 658-61.
- Powell, R.D. et al. (2011) J Biol Chem 286, 43596-600.
- Goldstone, D.C. et al. (2011) Nature 480, 379-82.
- Lahouassa, H. et al. (2012) Nat Immunol 13, 223-8.
- Yan, J. et al. (2013) J Biol Chem 288, 10406-17.
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