Render Target: STATIC
Render Timestamp: 2024-11-21T12:53:42.943Z
Commit: 5c4accf06eb7154018ba3f54329c7590f97f534a
XML generation date: 2024-09-30 01:59:57.205
Product last modified at: 2024-10-17T20:00:10.081Z
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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

UQCRC2 (F8Y5N) Rabbit mAb #99258

Filter:
  • WB
  • IP

    Supporting Data

    REACTIVITY H M R
    SENSITIVITY Endogenous
    MW (kDa) 48
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IP-Immunoprecipitation 
    Species Cross-Reactivity Key:
    • H-Human 
    • M-Mouse 
    • R-Rat 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Simple Western™ 1:50 - 1:250
    Immunoprecipitation 1:50

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    UQCRC2 (F8Y5N) Rabbit mAb recognizes endogenous levels of total UQCRC2 protein.

    Species Reactivity:

    Human, Mouse, Rat

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human UQCRC2 protein.

    Background

    Ubiquinol-cytochrome c reductase complex core protein 2 (UQCRC2), also known as cytochrome b-c1 complex subunit 2, is a component of the ubiquinol-cytochrome c oxidoreductase complex (Complex III) in the mitochondrial electron transport chain (1,2). Studies show that AMPK increases UQCRC2 expression to promote mitophagy, protecting the liver against alcohol-induced injury (3). In addition, overexpression of UQCRC2 was shown to inhibit gastric cancer cell proliferation, invasion, and migration (4).
    For Research Use Only. Not For Use In Diagnostic Procedures.
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