Wnt5a/b (C27E8) Rabbit mAb #2530
- WB
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 45 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Wnt-5a has been shown to signal through the canonical Wnt pathways as well as through non-canonical pathways and is up-regulated in various types of human cancers (6-8). In melanoma, Wnt5a is thought to directly affect cell motility and metastasis (9).
- Cadigan, K.M. and Nusse, R. (1997) Genes Dev. 11, 3286-3305.
- Moon, R.T. et al. (1997) Trends Genet. 13, 157-162.
- Kohn, A.D. and Moon, R.T. (2004) Cell Calcium 38, 439-446.
- Logan, C.Y. and Nusse, R. (2004) Annu. Rev. Cell Dev. Biol. 20, 781-810.
- Giles, R.H. et al. (2003) Biochim. Biophys. Acta. 1653, 1-24.
- Mikels, A.J. and Nusse, R. (2006) PLoS Biol. 4, e115.
- Katoh, M. and Katoh, M. (2007) Int. J. Mol. Med. 19, 273-278.
- Katoh, M. (2005) Oncol. Rep. 14, 1583-1588.
- Weeraratna, A.T. et al. (2002) Cancer Cell 1, 279-288.
Limited Uses
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