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Render Timestamp: 2024-12-23T11:25:32.702Z
Commit: f2d32940205a64f990b886d724ccee2c9935daff
XML generation date: 2024-09-20 06:22:46.585
Product last modified at: 2024-12-17T19:03:34.229Z
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PDP - Template Name: Chemical Modulators
PDP - Template ID: *******c501c72
  1. Products /
  2. Proteomic Analysis Products /
  3. Iodoacetamide, PTMScan® Qualified

Iodoacetamide, PTMScan® Qualified #88931

    Product Information

    Product Usage Information

    1. Weigh out 95mg of iodoacetamide and protect from light.

    2. Add reverse osmosis deionized (RODI) water or equivalent to a final volume of 5 ml immediately before use.

    Note: The iodoacetamide solution should be prepared fresh prior to each experiment.

    Storage

    Store lyophilized powder at 4°C, desiccated and protected from light.

    Product Description

    Iodoacetamide is recommended for use in our PTMScan® protocols when making tissue or cell lysates just prior to the digestion steps.
    Purity Greater than or equal to 99%
    Molecular Formula C2H4INO

    Background

    Iodoacetamide is a useful alkylating reagent that modifies cysteine residues so that they can no longer create disulfide linkages. This prevents proteins from refolding and helps to keep them in their primary linear structure to better enable protease digestion and peptide sequencing. This is an irreversible reaction and can also be used for inactivation of enzymes or improved resolution by electrophoresis, where disulfide bonds could potentially reform.

      Limited Uses

      Except as otherwise expressly agreed in a writing signed by a legally authorized representative of CST, the following terms apply to Products provided by CST, its affiliates or its distributors. Any Customer's terms and conditions that are in addition to, or different from, those contained herein, unless separately accepted in writing by a legally authorized representative of CST, are rejected and are of no force or effect.

      Products are labeled with For Research Use Only or a similar labeling statement and have not been approved, cleared, or licensed by the FDA or other regulatory foreign or domestic entity, for any purpose. Customer shall not use any Product for any diagnostic or therapeutic purpose, or otherwise in any manner that conflicts with its labeling statement. Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, prophylactic or therapeutic purposes, or any purchase of Product for resale (alone or as a component) or other commercial purpose, requires a separate license from CST. Customer shall (a) not sell, license, loan, donate or otherwise transfer or make available any Product to any third party, whether alone or in combination with other materials, or use the Products to manufacture any commercial products, (b) not copy, modify, reverse engineer, decompile, disassemble or otherwise attempt to discover the underlying structure or technology of the Products, or use the Products for the purpose of developing any products or services that would compete with CST products or services, (c) not alter or remove from the Products any trademarks, trade names, logos, patent or copyright notices or markings, (d) use the Products solely in accordance with CST Product Terms of Sale and any applicable documentation, and (e) comply with any license, terms of service or similar agreement with respect to any third party products or services used by Customer in connection with the Products.

      For Research Use Only. Not For Use In Diagnostic Procedures.
      Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc.
      PTMScan is a registered trademark of Cell Signaling Technology, Inc.
      All other trademarks are the property of their respective owners. Visit our Trademark Information page.