Analytical Tools to Evaluate CAR-T Cell Signaling & Activation

CAR-T cell activation is crucial for the success of CAR-T cell therapy as it allows the engineered T cells to effectively recognize, target, and eliminate cancer cells.

In this webinar, our two panelists will discuss a streamlined workflow to engineer and characterize CAR-T cell signaling and activation status, revealing the kinetics of CAR-T cell activation and signal transduction with reproducible quantification.

In this webinar, you'll learn:

• How the novel workflow provides granular time course information on CAR-T cell signaling and activation using just a few microliters of sample with hands-free automation.
• How anti-CAR linker antibodies can be used to confirm CAR expression, regardless of CAR antigen specificity, using both flow cytometry and capillary immunoassay read-outs.
• How to get detailed kinetics of CAR trafficking and intracellular CAR-T cell signaling events with reproducible quantitation.
• How to characterize CAR-T cell activation with simultaneous quantification of 4 secreted cytokines in a single 90-minute run.

Visit the CAR-T Therapy Research Tools page to find out more.