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PDP - Template Name: Monoclonal Antibody
PDP - Template ID: *******c5e4b77
R Recombinant
Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

ARPC5 (F5F6V) Rabbit mAb #48913

Filter:
  • WB
Western Blotting Image 1: ARPC5 (F5F6V) Rabbit mAb
Western blot analysis of extracts from various cell lines using ARPC5 (F5F6V) Rabbit mAb (upper) or GAPDH (D16H11) XP® Rabbit mAb #5174 (lower). Low expression of ARPC5 protein in VCaP, mES, and Renca cells is consistent with the predicted expression pattern.

To Purchase # 48913

Cat. # Size Qty. Price Ships
48913T 20 µl
$156
48913S 100 µl
$371

Supporting Data

REACTIVITY H M R
SENSITIVITY Endogenous
MW (kDa) 16
Source/Isotype Rabbit IgG
Application Key:
  • WB-Western Blotting 
Species Cross-Reactivity Key:
  • H-Human 
  • M-Mouse 
  • R-Rat 

Product Information

Product Usage Information

Application Dilution
Western Blotting 1:1000
Simple Western™ 1:10 - 1:50

Storage

Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

Protocol

Specificity / Sensitivity

ARPC5 (F5F6V) Rabbit mAb recognizes endogenous levels of total ARPC5 protein. This antibody cross-reacts with ARPC5L protein.

Species Reactivity:

Human, Mouse, Rat

Source / Purification

Monoclonal antibody is produced by immunizing animals with recombinant protein specific to full-length human ARPC5 protein.

Background

Actin-related protein 2/3 complex subunit 5 (ARPC5) is a component of the ARP2/3 actin nucleation complex, which regulates actin dynamics and cellular processes such as cell migration, division, endocytosis, and vesicle trafficking (1). The ARP2/3 complex has also been shown to promote repair of DNA double-strand breaks through homologous recombination (2). ARPC5 expression is increased and associated with poor prognosis in several human cancers, including hepatocellular carcinoma, prostate cancer, gliomas, and multiple myeloma (3-6).
For Research Use Only. Not For Use In Diagnostic Procedures.
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