PTMScan^® Pathway Service

PTMScan^® Pathways Services enable identification and quantification of hundreds to thousands of known protein targets within a specific pathway in response to a treatment or disease state. Experienced CST scientists utilize LC/MS based antibody array that combines antibody enrichment of post-translationally modified (PTM) peptides from defined pathways with LC-MS/MS, with complete results obtained in a single run.

You can follow-up on many of the candidate proteins identified via PTMScan® Pathway Services using modification state-specific and total protein antibodies from CST, which are produced and validated in-house for multiple applications.

CST also offers these additional pathway services:

• PTMScan® Direct Multi-Pathway Service - Targeted screening and quantification of a defined set of protein sites and signaling nodes critical for drug discovery, biomarker discovery, or diagnostic development.
• PTMScan^® Ser/Thr Kinases Service - Targeted screening and quantification of a defined set of protein sites within the Ser/Thr kinome.
• PTMScan^® Tyrosine Kinase Service - Targeted screening and quantification of a defined set of protein sites within the tyrosine kinase branch of the kinome.